I think PCR will stick around for a while, but you’re right — isothermal amplification and CRISPR diagnostics are making waves. Our lab actually tested a CRISPR-based kit last year and it was surprisingly simple, no thermocycler needed. That’s a big advantage for smaller labs or field testing. But the big hurdle is still validation and regulatory approval. We’ve had good luck sourcing updated kits and tools from https://gentaur.co.uk/ , since they keep track of emerging technologies alongside the traditional ones. It feels like we’re slowly moving toward a mix of platforms rather than one single “replacement.”